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Israel and Hamas agreed to a cease-fire Wednesday, ending eight days of fighting that killed more than 140 Palestinians and five Israelis.

“The United States welcomes the agreement today for the cease-fire in Gaza,” U.S. Secretary of State Hillary Clinton said at a news conference alongside Egyptian Foreign Minister Mohamed Kamel Amr. “This is a critical moment for the region.”

The cease-fire started at 9 p.m. Cairo time (2 p.m. ET).

Clinton thanked Egypt’s Islamist President Mohammed Morsi for his mediation efforts and pledged to work with partners in the region “to consolidate this progress, improve conditions for the people of Gaza, provide security for the people of Israel.”

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